Cardiac Arrest in Pregnancy: An 2019 UPDATE

Sometimes we need a reminder and update on the basics… Your Welcome.. Cardiac arrest in pregnancy. SEMINARS IN PERINATOLOGY 42(2018)33–38.  https://doi.org/10.1053/j.semperi.2017.11.007 MATERNAL PHYSIOLOGY – The maternal heart rate increases by 20–30% or 15–20 beats per minute – Cardiac output increases by 30–50% or 1.8 L per minute with the uterus receiving approximately 17% of maternal cardiac […]

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Fill the Tank or Rev’ the Engine… WHOA, PUMP the BRAKES: Early fixed dose norepi for septic shock?

We all know hypotension is bad. But should we fill with fluids or rev up the heart with pressors. This begs the question does early norepi help prevent hypotension and mortality? Today’s quick hit article: Permpikul C, et al. Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER) : A Randomized Trial. Am J Respir Crit Care Med. 2019 Feb 1. doi: 10.1164/rccm.201806-1034OC. PMID 30704260. […]

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Lactate for Safely Screening Sepsis?

Fernando  et. al.  HELPFUL ONLY WHEN ELEVATED: INITIAL SERUM LACTATE IN STABLE EMERGENCY DEPARTMENT PATIENTS WITH SEPSIS IS SPECIFIC, BUT NOT SENSITIVE FOR FUTURE DETERIORATION Journal of Emergency Medicine, Vol. 54, No. 6, pp. 766–773. https://doi.org/10.1016/j.jemermed.2018.01.040  BOTTOM LINE: A lactate >4 in this prospective observational cohort study of almost 1000 patients with the “CMS” definition […]

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Antibiotic StewardSHIP…Moveover Titanic…there’s a new failure in town.

Tamma, et al. Rethinking How Antibiotics Are Prescribed: Incorporating the 4 Moments of Antibiotic Decision Making Into Clinical Practice. JAMA. 2018 Dec 27. doi: 10.1001/jama.2018.19509. [Epub ahead of print]   BOTTOM LINE: Providers should be asking themselves: “What is the likelihood my patient has an infection and that it requires antibiotic therapy?” Those who know […]

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SO YOU THINK YOU KNOW CELLULITIS?

Sometimes things aren’t as they seem.  As an attending I often hear from a resident “Hey got an easy one for ya, 50 y/o diabetic with bilateral cellulitis vanc given, I’ll get some admit labs” followed by a precipitous mic drop. I was told once that a good attending “makes a difficult case simple and […]

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SUP-ICU Trial: Pantoprazole in patients at risk for Gastrointestinal Bleeding

SUP-ICU Trial Kart, M. Pantoprazole in patients at risk for Gastrointestinal Bleeding in the ICU. N Engl J Med 2018;379:2199-208. Trial done in the UK. It was a multicenter, stratified, parallel group, placebo controlled blinded randomized trial.  Included pts admitted to the ICU who were 18 yo or older and had at least one risk […]

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